What is immunoglobulin nephropathy?

IgA nephropathy is known as Berger’s disease. It is a kidney-related disorder that develops when IgA deposits itself into the kidneys and inflames and damages the tissues within. IgA or immunoglobulin is an antibody, a type of protein the work of which is to save and protect the body against infections. It is co-produced by the immune system to help the body fight against foreign substances.


To treat IgA nephropathy, you will need to consult a nephrologist, a doctor who specializes in the kidney-related disorder.

How IgA damages the kidneys?

IgA nephropathy impairs kidney function by damaging the filters called glomeruli in the first place. Glomeruli are the capillaries within the kidneys that remove waste and extra fluid from the blood. The buildup of IgA may lead to nephrons being scarred and low kidney function over time. Years later, if a cure for IgA nephropathy in Ayurveda is not taken, it may even progress to end-stage renal disease. At that time, the kidneys wholly lose their ability to function properly and unsafe levels of waste and fluid may accumulate in the bloodstream as a consequence.

What may be the causes of IgA damaging the kidney function?

Clinical trials confirm that IgA nephropathy is an autoimmune disease caused by damage to the immune system of the body that in return harm the kidney function. People with IgA nephropathy may have an increased level of IgA in the body. This IgA contains less galactose than normally anyone has when they are healthy. Since other antibodies may not recognize this galactose deficient IgA, they attach themselves to it and cause clumps. Such clumps are called immune complex which ought to cause inflammation in the kidney’s filters.

In other cases, IgA nephropathy may run in families. Scientists have found a connection between genes and their role in the development of IgA nephropathy.

More or fewer cases of IgA can be linked to infections in the body and the body’s immune responses to these infections.

Other potential causes of IgA nephropathy may include:

• Liver disease: Scarring of the tissue may replace normal tissues within the liver and cause IgA. Examples include chronic hepatitis B and C infections.
• Infections: These include HIV and some bacterial infections.

Risk factors related to IgA nephropathy:

Some factors might play a role in the development of IgA nephropathy, these may include:

• Gender
• Ethnicity
• Age
• A family history of IgA nephropathy

What may be the complications of IgA nephropathy?

How IgA nephropathy affects the body may vary from person to person. Some people do not notice any sign until the very last time and in more or fewer cases, people may develop a following of the following complications:

Chronic kidney disease: IgA nephropathy may slowly affect kidney function and later on the kidney may stop functioning at all. To cure this, they need to go for IgA nephropathy ayurvedic treatment.

High blood pressure: Damage to the kidneys when IgA inflames the filters can raise your blood pressure. Blood pressure can further be a problem to your kidneys as it damages the blood vessels needed for the filtration process.

High cholesterol level: High levels of cholesterol can damage the heart along with the kidneys.

Acute kidney failure: If your kidneys lose their filtering capacity, they may fail at all.

Nephrotic syndrome: If your kidney function gets disturbed, glomeruli results in high protein levels, high cholesterol, and lipids, swelling in the body, feet, and eyes.

What signs may appear during IgA nephropathy?

In the initial trials, IgA nephropathy may not cause any sign and remain silent for eons. If anyway you notice symptoms, it may be like hematuria or blood in the urine. Hematuria appears when the glomeruli are not able to function properly resulting in leakage of blood along with it.

There are two types of hematuria based on how the blood is visible:

Microscopic hematuria: Microscopic hematuria means that the blood can only be seen with a microscope.

Gross hematuria: Gross hematuria means the urine appears red or dark-colored even with the naked eye.

Another symptom of IgA nephropathy is albuminuria. When the glomeruli do not work, the person's urine may have protein instances just like blood. This makes the urine foamy and frothy. Healthy kidneys make proteins from skipping into the blood, but damaged glomeruli may allow the situation to go worse.

After 10 to 20 years with IgA nephropathy, most people develop end-stage kidney disease.

The signs and symptoms that may preexist at that time include:

• high blood pressure
• little or no urine at all
• edema
• feeling tired and drowsiness
• generalized itching or numbness in the body
• dry skin
• headaches
• weight loss
• appetite loss
• nausea and vomiting
• sleep issues because of waste buildup
• trouble concentrating
• darkened skin
• muscle cramps
• anemia
• malnutrition

Treatment of IgA nephropathy

There is no allopathic treatment to control IgA nephropathy and only preventive measures. Researchers have not yet found a specific cure because they believe when the kidneys are damaged they cannot be prevented.

But there is a cure for IgA nephropathy in Ayurveda. Ayurvedic medicines are very helpful in preventing inflammation within the kidneys because they have potent properties. Many herbs are very powerful in terms of anti-inflammatory, diuretics, cancer-preventing, and anti-oxidants properties. You will notice your health getting better with the ayurvedic medicines and changes in your present-day diet.

A good nephrologist will also suggest a renal friendly diet to make sure your kidneys are not overburdened. And this is far the best methodology to work for IgA nephropathy and any kidney disease.

For more information on the treatment, you can consult eminent doctors at Karma Ayurveda Health.

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